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Tebentafusp (IMCgp100), a first in class immune-mobilizing monoclonal T-cell receptors against cancer (ImmTAC) for HLA-A*02:01 positive uveal melanoma: Product review

Tebentafusp (IMCgp100, Kimmtrak) is a first-in-class Immune mobilizing monoclonal T-cell receptors against cancer (ImmTAC). ImmTAC are fusion proteins comprising an affinity-enhanced soluble T-cell receptor (TCR) against a specific peptide-HLA complex and an anti-CD3 single-chain variable fragment (...

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Principais autores: Jonathan E. Cohen, Inderjit Mehmi, Mordechai Avner, Justin Moyers, Omid Hamid
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2026-12-01
Serier:Human Vaccines & Immunotherapeutics
Fag:
Uveal melanoma
cancer immunotherapy
Immune-mobilizing monoclonal T-cell receptors against cancer (ImmTAC)
T-cell receptor (TCR)
human leukocyte antigen (HLA)
Online adgang:https://www.tandfonline.com/doi/10.1080/21645515.2026.2675068
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