Malignant H1299 tumour cells preferentially internalize iron-bound inositol hexakisphosphate

In colon enterocytes and in well-differentiated colon cancer CaCo-2 cells, InsP6 (inositol hexakisphosphate) inhibits iron uptake by forming extracellular insoluble iron/InsP6 complexes. In this study, we confirmed that CaCo-2 cells are not able to take up iron/InsP6 but, interestingly, found that t...

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Autors principals:	Sabine Windhorst, Georg W. Mayr, Peter Nielsen, Michaela Schweizer, Hongying Lin, Christine Blechner, Christina Helmis
Format:	Artigo
Idioma:	Inglês
Publicat:	Portland Press 2013-10-01
Col·lecció:	Bioscience Reports
Matèries:	H1299 tumour cell inositol hexakisphosphate multiple-inositol-polyphosphate-phosphatase (MINPP1)
Accés en línia:	http://www.bioscirep.org/bsr/033/e075/bsr033e075.htm
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