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The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tethering

Cohesin tethers together regions of DNA, thereby mediating higher order chromatin organization that is critical for sister chromatid cohesion, DNA repair and transcriptional regulation. Cohesin contains a heterodimeric ATP-binding Cassette (ABC) ATPase comprised of Smc1 and Smc3 ATPase active sites....

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Autori principali: Gamze Çamdere, Vincent Guacci, Jeremiah Stricklin, Douglas Koshland
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications Ltd 2015-11-01
Serie:eLife
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Accesso online:https://elifesciences.org/articles/11315
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