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The aryl hydrocarbon receptor: structure, signaling, physiology and pathology

Abstract The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor of the bHLH/PAS protein family. In this review, we explore the multifaceted roles of AHR in both health and disease, tracing its recognition as a xenobiotic sensor and a central regulator of physiological homeost...

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Detalhes bibliográficos
Principais autores: Xavier Coumoul, Robert Barouki, Charlotte Esser, Thomas Haarmann-Stemmann, B. Paige Lawrence, Jörg Lehmann, Pedro Moura-Alves, Iain A. Murray, Christiane A. Opitz, Gary H. Perdew, William Bourguet
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2026-01-01
Colecção:Signal Transduction and Targeted Therapy
Acesso em linha:https://doi.org/10.1038/s41392-025-02500-8
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