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Environmental Factors Modulate the Role of <i>orf21</i> Sigma Factor in Clavulanic Acid Production in <i>Streptomyces Clavuligerus</i> ATCC27064

Sigma factors and sigma factor-related mechanisms control antibiotic production in <i>Streptomyces</i>. In this contribution, the <i>orf21</i> gene was overexpressed in the wild-type strain of <i>Streptomyces clavuligerus</i> ATCC2764, yielding <i>S. clavuligerus</i>/pIORF21, to further evaluate its...

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Main Authors: Luisa F. Patiño, Vanessa Aguirre-Hoyos, Laura I. Pinilla, León F. Toro, Rigoberto Ríos-Estepa
Format: Artigo
Language:Inglês
Published: MDPI AG 2022-02-01
Series:Bioengineering
Subjects:
<i>Streptomyces clavuligerus</i>
clavulanic acid
sigma factors
gene expression
Online Access:https://www.mdpi.com/2306-5354/9/2/78
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