In vivo trafficking of a tumor-targeting IgE antibody: molecular imaging demonstrates rapid hepatobiliary clearance compared to IgG counterpart

IgE antibodies elicit powerful immune responses, recruiting effector cells to tumors more efficiently and with greater cytotoxicity than IgG antibodies. Consequently, IgE antibodies are a promising alternative to conventional IgG-based therapies in oncology (AllergoOncology). As the pharmacokinetics...

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Autors principals:	Francis Man, Alexander Koers, Panagiotis Karagiannis, Debra H. Josephs, Heather J. Bax, Amy E. Gilbert, Tihomir S. Dodev, Silvia Mele, Giulia Chiaruttini, Silvia Crescioli, Jitesh Chauhan, Julia E. Blower, Margaret S. Cooper, James Spicer, Sophia N. Karagiannis, Philip J. Blower
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis Group 2021-01-01
Col·lecció:	OncoImmunology
Matèries:	ige igg allergooncology allergoimmunology spect nuclear imaging molecular imaging cancer immunotherapy
Accés en línia:	http://dx.doi.org/10.1080/2162402X.2021.1966970
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