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Molecular Dynamics to Elucidate the DNA-Binding Activity of AlpZ, a Member of the Gamma-Butyrolactone Receptor Family in Streptomyces ambofaciens

Signaling molecule receptors play a central role in quorum sensing and in the coordination onset of specialized metabolite biosynthesis in Streptomyces due to their dual function in signal detection and gene expression control through DNA-binding in the promoter region of their target genes. In Stre...

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Principais autores: Cláudia M. Vicente, Jean-Michel Girardet, Laurence Hôtel, Bertrand Aigle
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Microbiology
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Acceso en liña:https://www.frontiersin.org/article/10.3389/fmicb.2020.01255/full
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