Preclinical Validation of the Heparin-Reactive Peptide p5+14 as a Molecular Imaging Agent for Visceral Amyloidosis

Amyloid is a complex pathologic matrix comprised principally of paracrystalline protein fibrils and heparan sulfate proteoglycans. Systemic amyloid diseases are rare, thus, routine diagnosis is often challenging. The glycosaminoglycans ubiquitously present in amyloid deposits are biochemically and e...

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Detalhes bibliográficos

Principais autores:	Jonathan S. Wall, Emily B. Martin, Tina Richey, Alan C. Stuckey, Sallie Macy, Craig Wooliver, Angela Williams, James S. Foster, Penney McWilliams-Koeppen, Ed Uberbacher, Xiaolin Cheng, Stephen J. Kennel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2015-04-01
Colecção:	Molecules
Assuntos:	glycosaminoglycans amyloidosis peptide imaging modeling SPECT p5+14
Acesso em linha:	http://www.mdpi.com/1420-3049/20/5/7657
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