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Contribution of the different Neisseria gonorrhoeae lipooligosaccharide structural variants to functional responses elicited by GMMA outer membrane vesicles

Abstract Despite decades of research, an effective vaccine against Neisseria gonorrhoeae remains elusive due to the pathogen's antigenic variability and immune evasion capabilities. Retrospective studies of OMV-based meningococcal vaccines have shown a partial effectiveness against gonorrhea, reigni...

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Hlavní autoři: R. Cuffaro, G. Buffi, G. Romagnoli, M. Giuliani, D. Proietti, M. Zambelli, M. Spinsanti, A. G. O. Manetti, M. Fabbrini, S. Savino, G. Giordano, I. Delany, E. Bartolini, S. Ram, M. R. Romano, I. Margarit, F. Carboni
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2025-10-01
Edice:npj Vaccines
On-line přístup:https://doi.org/10.1038/s41541-025-01271-1
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