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The GET pathway is a major bottleneck for maintaining proteostasis in Saccharomyces cerevisiae

Abstract A hallmark of aging in a variety of organisms is a breakdown of proteostasis and an ensuing accumulation of protein aggregates and inclusions. However, it is not clear if the proteostasis network suffers from a uniform breakdown during aging or if some distinct components act as bottlenecks...

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Detaylı Bibliyografya
Asıl Yazarlar: Rebecca Josefson, Navinder Kumar, Xinxin Hao, Beidong Liu, Thomas Nyström
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Portfolio 2023-06-01
Seri Bilgileri:Scientific Reports
Online Erişim:https://doi.org/10.1038/s41598-023-35666-8
Etiketler: Etiketle
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