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Screening of a Focused Ubiquitin-Proteasome Pathway Inhibitor Library Identifies Small Molecules as Novel Modulators of Botulinum Neurotoxin Type A Toxicity

Botulinum neurotoxins (BoNTs) are known as the most potent bacterial toxins, which can cause potentially deadly disease botulism. BoNT Serotype A (BoNT/A) is the most studied serotype as it is responsible for most human botulism cases, and its formulations are extensively utilized in clinics for the...

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Бібліографічні деталі
Автори: Edanur Sen, Krishna P. Kota, Rekha G. Panchal, Sina Bavari, Erkan Kiris
Формат: Artigo
Мова:Inglês
Опубліковано: Frontiers Media S.A. 2021-09-01
Серія:Frontiers in Pharmacology
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Онлайн доступ:https://www.frontiersin.org/articles/10.3389/fphar.2021.763950/full
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