RUNX1 mutations in cytogenetically normal acute myeloid leukemia are associated with a poor prognosis and up-regulation of lymphoid genes

Background The RUNX1 (AML1) gene is a frequent mutational target in myelodysplastic syndromes and acute myeloid leukemia. Previous studies suggested that RUNX1 mutations may have pathological and prognostic implications.Design and Methods We screened 93 patients with cytogenetically normal acute mye...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Philipp A. Greif, Nikola P. Konstandin, Klaus H. Metzeler, Tobias Herold, Zlatana Pasalic, Bianka Ksienzyk, Annika Dufour, Friederike Schneider, Stephanie Schneider, Purvi M. Kakadia, Jan Braess, Maria Cristina Sauerland, Wolfgang E. Berdel, Thomas Büchner, Bernhard J. Woermann, Wolfgang Hiddemann, Karsten Spiekermann, Stefan K. Bohlander
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Ferrata Storti Foundation 2012-12-01
coleção:	Haematologica
Acesso em linha:	https://haematologica.org/article/view/6508
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!