Substantial Effect of Efavirenz Monotherapy on Bilirubin Levels in Healthy Volunteers

Background: Efavirenz exhibits multiple interactions with drug-metabolizing enzymes and transporters, and for this reason efavirenz-based HIV therapy is associated with altered pharmacokinetics of coadministered drugs. Probably by the same mechanism, efavirenz-based HIV therapy affects the dispositi...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Ingrid F. Metzger, PhD, Troy C. Quigg, MD, Noam Epstein, Abdulateef O. Aregbe, MD, Nancy Thong, John T. Callaghan, MD, PhD, David A. Flockhart, MD, PhD, Anne T. Nguyen, Colleen K. Stevens, Samir K. Gupta, Zeruesenay Desta, PhD
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2014-12-01
Цуврал:	Current Therapeutic Research
Нөхцлүүд:	anemia bilirubin disposition drug interactions efavirenz monotherapy neutropenia
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S0011393X14000095
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!