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The cGAS-STING signaling pathway: emerging targets and challenges in breast cancer immunotherapy

The cGAS-STING signaling pathway serves as a crucial bridge between innate and adaptive immunity, playing a dual role in breast cancer pathogenesis and treatment. This review delves into its complex functions within the breast tumor microenvironment, where pathway activation can either stimulate pot...

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Gardado en:
Principais autores: Lei Sun, Jing Chen, Shiyan Zeng
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2026-01-01
Series:Frontiers in Immunology
Assuntos:
biomarker discovery
breast cancer
cGAS-STING
combination therapy
immunotherapy
immunotherapy resistance
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1685931/full
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