Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment
Abstract Claudins are a 27-member family of ~25 kDa membrane proteins that integrate into tight junctions to form molecular barriers at the paracellular spaces between endothelial and epithelial cells. As the backbone of tight junction structure and function, claudins are attractive targets for modu...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2024-06-01
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| coleção: | Communications Biology |
| Acesso em linha: | https://doi.org/10.1038/s42003-024-06437-6 |
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