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A transcriptomics approach to expand therapeutic options and optimize clinical trials in oncology

Background: The current model of clinical drug development in oncology displays major limitations due to a high attrition rate in patient enrollment in early phase trials and a high failure rate of drugs in phase III studies. Objective: Integrating transcriptomics for selection of patients has the p...

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Autors principals: Vladimir Lazar, Baolin Zhang, Shai Magidi, Christophe Le Tourneau, Eric Raymond, Michel Ducreux, Catherine Bresson, Jacques Raynaud, Fanny Wunder, Amir Onn, Enriqueta Felip, Josep Tabernero, Gerald Batist, Razelle Kurzrock, Eitan Rubin, Richard L. Schilsky
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publishing 2023-03-01
Col·lecció:Therapeutic Advances in Medical Oncology
Accés en línia:https://doi.org/10.1177/17588359231156382
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