Characterization of methadone as a β-arrestin-biased μ-opioid receptor agonist
Background Methadone is a unique µ-opioid receptor agonist. Although several researchers have insisted that the pharmacological effects of methadone are mediated through the blockade of NMDA receptor, the underlying mechanism by which methadone exerts its distinct pharmacological effects compared to...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
SAGE Publishing
2016-06-01
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| Serie: | Molecular Pain |
| Accesso online: | https://doi.org/10.1177/1744806916654146 |
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