Atypical electrophysiological and behavioral responses to diazepam in a leading mouse model of Down syndrome

Abstract Mounting evidence implicates dysfunctional GABAAR-mediated neurotransmission as one of the underlying causes of learning and memory deficits observed in the Ts65Dn mouse model of Down syndrome (DS). The specific origin and nature of such dysfunction is still under investigation, which is an...

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Principais autores:	Daniella B. Victorino, Daniel J. L. L. Pinheiro, Jonah J. Scott-McKean, Sarah Barker, Melissa R. Stasko, Jean Faber, Carla A. Scorza, Alberto C. S. Costa
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2021-05-01
coleção:	Scientific Reports
Acesso em linha:	https://doi.org/10.1038/s41598-021-89011-y
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