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Targeting AGTPBP1 inhibits pancreatic cancer progression via regulating microtubules and ERK signaling pathway

Abstract Background AGTPBP1 is a cytosolic carboxypeptidase that cleaves poly-glutamic acids from the C terminus or side chains of α/β tubulins. Although its dysregulated expression has been linked to the development of non-small cell lung cancer, the specific roles and mechanisms of AGTPBP1 in panc...

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Autors principals: Ding-zhong Li, Zhe-yu Yang, Asi leng, Qian Zhang, Xiao-dong Zhang, Yan-chao Bian, Rui Xiao, Jian-jun Ren
Format: Artigo
Idioma:Inglês
Publicat: BMC 2024-08-01
Col·lecció:Molecular Medicine
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Accés en línia:https://doi.org/10.1186/s10020-024-00892-x
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