Analysis of germline-driven ancestry-associated gene expression in cancers

Summary: Differential mRNA expression between ancestry groups can be explained by both genetic and environmental factors. We outline a computational workflow to determine the extent to which germline genetic variation explains cancer-specific molecular differences across ancestry groups. Using multi...

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Príomhchruthaitheoirí:	Nyasha Chambwe, Rosalyn W. Sayaman, Donglei Hu, Scott Huntsman, Anab Kemal, Samantha Caesar-Johnson, Jean C. Zenklusen, Elad Ziv, Rameen Beroukhim, Andrew D. Cherniack, Jian Carrot-Zhang, Ashton C. Berger, Seunghun Han, Matthew Meyerson, Jeffrey S. Damrauer, Katherine A. Hoadley, Ina Felau, John A. Demchok, Michael K.A. Mensah, Roy Tarnuzzer, Zhining Wang, Liming Yang, Theo A. Knijnenburg, A. Gordon Robertson, Christina Yau, Christopher Benz, Kuan-lin Huang, Justin Y. Newberg, Garrett M. Frampton, R. Jay Mashl, Li Ding, Alessandro Romanel, Francesca Demichelis, Wanding Zhou, Peter W. Laird, Hui Shen, Christopher K. Wong, Joshua M. Stuart, Alexander J. Lazar, Xiuning Le, Ninad Oak
Formáid:	Artigo
Teanga:	Inglês
Foilsithe / Cruthaithe:	Elsevier 2022-09-01
Sraith:	STAR Protocols
Ábhair:	Bioinformatics Sequence analysis Cancer Genomics RNAseq Gene Expression
Rochtain ar líne:	http://www.sciencedirect.com/science/article/pii/S266616672200466X
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Analysis of germline-driven ancestry-associated gene expression in cancers

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