Sex-specific differences in preclinical models of advanced chronic liver disease and portal hypertension

Abstract Background Chronic liver disease is a major health concern, but sex-specific differences in its pathophysiology remain unclear. Preclinical studies have predominantly used male animals, limiting findings' relevance to both sexes. This project aimed to explore sex differences in cirrhosis an...

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Detalhes bibliográficos

Principais autores:	Peio Aristu-Zabalza, María Andrés-Rozas, Zoe Boyer-Díaz, David P. Al-Adra, Douglas Maya-Miles, Sergi Guixé-Muntet, Anabel Fernández-Iglesias, Jordi Gracia-Sancho
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-06-01
coleção:	Biology of Sex Differences
Assuntos:	Hepatic hemodynamic Sinusoidal cells Gender Liver transcriptomics Cirrhosis
Acesso em linha:	https://doi.org/10.1186/s13293-025-00721-8
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