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Iron Chelation Prevents Age‐Related Skeletal Muscle Sarcopenia in Klotho Gene Mutant Mice, a Genetic Model of Aging

ABSTRACT Background A decline in skeletal muscle mass and function known as skeletal muscle sarcopenia is an inevitable consequence of aging. Sarcopenia is a major cause of decreased muscle strength, physical frailty and increased muscle fatigability, contributing significantly to an increased risk...

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Principais autores: Chhanda Bose, Judit Megyesi, Oleg Karaduta, Sharda P. Singh, Sundararaman Swaminathan, Sudhir V. Shah
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2025-02-01
coleção:Journal of Cachexia, Sarcopenia and Muscle
Assuntos:
catalytic iron
deferiprone
klotho
myostatin
skeletal muscle sarcopenia
Acesso em linha:https://doi.org/10.1002/jcsm.13678
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