The discovery of small-molecule inhibitors of cFLIP that sensitise tumour cells to TNF-related apoptosis-inducing ligand

The TNF-related apoptosis-inducing ligand (TRAIL) has potential as a therapeutic agent, as it has previously been shown to induce apoptosis in triple-negative breast cancer. However, several studies have demonstrated that patients with tumours develop resistance to TRAIL. We have previous...

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Hlavní autoři:	Gilda Giancotti, Rhiannon French, Olivia Hayward, Kok Yung Lee, Timothy Robinson, Andreia M. Ribeiro da Silva, Athina Varnava, Marion MacFarlane, Richard W. E. Clarkson, Andrew D. Westwell, Andrea Brancale
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Academia.edu Journals 2025-04-01
Edice:	Academia Oncology
On-line přístup:	https://www.academia.edu/129090477/The_discovery_of_small_molecule_inhibitors_of_cFLIP_that_sensitise_tumour_cells_to_TNF_related_apoptosis_inducing_ligand
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