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SUMOylation is essential for Sirt2 tumor-suppressor function in neuroblastoma

SUMOylation is an important post-translational modification that participates in a variety of cellular physiological and pathological processes in eukaryotic cells. Sirt2, a NAD+-dependent deacetylase, usually exerts a tumor-suppressor function. However, the role of SUMOylation in cancer cells is no...

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Principais autores: Wenmei Lu, Qian Wang, Ci Xu, Haihua Yuan, Qiang Fan, Biying Chen, Renjie Cai, Danhong Wu, Ming Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021-01-01
coleção:Neoplasia: An International Journal for Oncology Research
Assuntos:
Sirt2
SUMOylation
Acetylation
Cell Signaling
Neuroblastoma
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1476558620301810
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