XIST and MUC1-C form an auto-regulatory pathway in driving cancer progression

Abstract The long non-coding RNA X-inactive specific transcript (lncRNA XIST) and MUC1 gene are dysregulated in chronic inflammation and cancer; however, there is no known interaction of their functions. The present studies demonstrate that MUC1-C regulates XIST lncRNA levels by suppressing the RBM1...

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Hlavní autoři:	Keyi Wang, Atrayee Bhattacharya, Naoki Haratake, Tatsuaki Daimon, Ayako Nakashoji, Hiroki Ozawa, Bo Peng, Wei Li, Donald Kufe
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Publishing Group 2024-05-01
Edice:	Cell Death and Disease
On-line přístup:	https://doi.org/10.1038/s41419-024-06684-9
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