Is the Antidepressant Activity of Selective Serotonin Reuptake Inhibitors Mediated by Nicotinic Acetylcholine Receptors?

It is generally assumed that selective serotonin reuptake inhibitors (SSRIs) induce antidepressant activity by inhibiting serotonin (5-HT) reuptake transporters, thus elevating synaptic 5-HT levels and, finally, ameliorates depression symptoms. New evidence indicates that SSRIs may also modulate oth...

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Autores principales:	Hugo R. Arias, Katarzyna M. Targowska-Duda, Jesús García-Colunga, Marcelo O. Ortells
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2021-04-01
Colección:	Molecules
Materias:	selective serotonin reuptake inhibitors antidepressants nicotinic acetylcholine receptors noncompetitive antagonists neuronal pathways molecular modeling
Acceso en línea:	https://www.mdpi.com/1420-3049/26/8/2149
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