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The origin of the RB1 imprint.

The human RB1 gene is imprinted due to a differentially methylated CpG island in intron 2. This CpG island is part of PPP1R26P1, a truncated retrocopy of PPP1R26, and serves as a promoter for an alternative RB1 transcript. We show here by in silico analyses that the parental PPP1R26 gene is present...

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Bibliografski detalji
Glavni autori: Deniz Kanber, Karin Buiting, Christian Roos, Jörg Gromoll, Sabine Kaya, Bernhard Horsthemke, Dietmar Lohmann
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2013-01-01
Serija:PLoS ONE
Online pristup:http://europepmc.org/articles/PMC3839921?pdf=render
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