Airborne transmission-mediated delivery of a live-attenuated influenza virus vector-based intranasal COVID-19 vaccine protects Syrian hamsters against SARS-CoV-2 challenge

Abstract Given their critical role in eliciting respiratory immunity, mucosal SARS-CoV-2 vaccines receive significant research attention. Our previous phase 1/2 trial revealed that aerosolized live-attenuated vectored influenza virus COVID-19 vaccine likely elicited specific cellular immunity and we...

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Detalhes bibliográficos

Principais autores:	Yaode Chen, Limin Zhang, Congjie Chen, Lunzhi Yuan, Qiangyuan Han, Xijing Wang, Heming Chen, Xiangjie Chen, Ruotong Wu, Zeheng Li, Lingyu Han, Zhen Lu, Dongmei Wei, Ningshao Xia, Junyu Chen, Yixin Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-12-01
Colecção:	npj Vaccines
Acesso em linha:	https://doi.org/10.1038/s41541-025-01332-5
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