Case Report: Lasting complete response to pembrolizumab in mismatch repair-deficient cardiac sarcoma: a genomic characterization

Sarcomas are traditionally considered “cold” tumors with poor response to immunotherapy. However, evidence accumulating over the last years shows that immune checkpoint inhibitors (ICIs) may have a role in selected sarcoma patients according to predictive markers. Here, we report the case of a woman...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Daniela A. Ferraro, Bettina Bisig, David C. Rotzinger, Fresia Pareja, Edoardo Missiaglia, Ioannis Voutsadakis, Krisztian Homicsko, Antonia Digklia
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Frontiers Media S.A. 2025-04-01
Σειρά:	Frontiers in Oncology
Θέματα:	cardiac sarcoma immune-checkpoint inhibitors (ICI) complete response (CR) predictive markers mismatch repair deficiency (MMRd) microsatellite instability (MSI)
Διαθέσιμο Online:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1485386/full
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