Human umbilical cord mesenchymal stem cells reduce oxidative damage and apoptosis in diabetic nephropathy by activating Nrf2

Abstract Background Mesenchymal stem cells (MSCs) have a therapeutic effect on diabetic nephropathy (DN) but the underlying mechanism remains unclear. This study was conducted to investigate whether human umbilical cord-MSCs (hUCMSCs) can induce oxidative damage and apoptosis by activating Nrf2. Met...

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Principais autores:	Ping Nie, Xue Bai, Yan Lou, Yuexin Zhu, Shan Jiang, Lina Zhang, Na Tian, Ping Luo, Bing Li
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2021-08-01
Serija:	Stem Cell Research & Therapy
Teme:	Mesenchymal stem cell Oxidative damage Apoptosis Diabetic nephropathy Nrf2
Online dostop:	https://doi.org/10.1186/s13287-021-02447-x
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