Novel APC promoter 1B variant associated with gastric adenocarcinoma and proximal polyposis of the stomach: a case report

IntroductionGastric adenocarcinoma and proximal polyposis of the stomach (GAPPS) is a rare autosomal dominant familial gastric cancer syndrome. GAPPS is caused by pathogenic variant in the regulatory region of APC. This study describes the first Korean case of GAPPS associated with a novel likely pa...

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Bibliographic Details

Main Authors:	Jong Sun Park, Sun Gyo Lim, Jongmun Choi, Sae-Mi Lee, Chang Ahn Seol, Seon-Yong Jeong, Eunkuk Park, Young Bae Sohn
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2026-02-01
Series:	Frontiers in Genetics
Subjects:	regulatory region of APC promoter 1B c.-181dupC novel variant in vitro functional study
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2026.1695311/full
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