Targeted mutagenesis of ∆5 and ∆6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar)

Abstract Background With declining wild fish populations, farmed salmon has gained popularity as a source for healthy long-chain highly unsaturated fatty acids (LC-HUFA). However, the introduction of plant oil in farmed salmon feeds has reduced the content of these beneficial LC-HUFA. The synthetic...

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Principais autores:	Yang Jin, Alex K. Datsomor, Rolf E. Olsen, Jon Olav Vik, Jacob S. Torgersen, Rolf B. Edvardsen, Anna Wargelius, Per Winge, Fabian Grammes
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2020-11-01
Serija:	BMC Genomics
Teme:	Atlantic salmon CRISPR mosaicism Long-chain highly unsaturated fatty acids Fatty acid desaturase Sterol regulatory binding protein, exon skipping Transcriptional regulation
Online dostop:	http://link.springer.com/article/10.1186/s12864-020-07218-1
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