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Identification of neoepitope reactive T-cell receptors guided by HLA-A*03:01 and HLA-A*11:01 immunopeptidomics

Background Tumor-specific mutated proteins can create immunogenic non-self, mutation-containing ‘neoepitopes’ that are attractive targets for adoptive T-cell therapies. To avoid the complexity of defining patient-specific, private neoepitopes, there has been major interest in targeting common shared...

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Autori principali: Xu Zhang, Sudipto Das, Zhiya Yu, Ken-ichi Hanada, James C Yang, Thorkell Andresson, Catherine M Ade, Matthew J Sporn, Yue A Qi, Tapan Maity, Udayan Guha
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2023-09-01
Serie:Journal for ImmunoTherapy of Cancer
Accesso online:https://jitc.bmj.com/content/11/9/e007097.full
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