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Safety of Mechanically Fibrillated Cellulose Nanofibers (CNFs) by Inhalation Exposure Based on TG412

An investigation into the acute toxicity of mechanically fibrillated cellulose nanofibers (fib-CNFs), with a fiber length ranging from 500 to 600 nm, was conducted in accordance with the OECD TG412 guidelines. In this study, rats were exposed to fib-CNFs via nasal inhalation for 6 h daily over a 28-...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Yoshihiro Yamashita, Akinori Tokunaga, Koji Aoki, Tamotsu Ishizuka, Satoshi Fujita, Shuichi Tanoue
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2025-01-01
Schriftenreihe:Nanomaterials
Schlagworte:
OECD TG412
fib-CNFs
in-vivo
rat
inhalation exposure
NOAEL
Online-Zugang:https://www.mdpi.com/2079-4991/15/3/214
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