Influence of EGF and pro-NGF on EGFR/SORTILIN interaction and clinical impact in head and neck squamous cell carcinoma

Head and Neck Squamous Cell Carcinoma (HNSCC) remains a cancer with a poor prognosis, with a 5-year survival rate of less than 50%. Although epidermal growth factor receptor (EGFR) is almost always overexpressed, targeted anti-EGFR therapies have modest efficacy and are mainly used in palliative car...

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Autors principals:	Martin Morisse, Thomas Bourhis, Romain Lévêque, Mathieu Guilbert, Julien Cicero, Martine Palma, Dominique Chevalier, Xuefen le Bourhis, Robert-Alain Toillon, Francois Mouawad
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2023-07-01
Col·lecció:	Frontiers in Oncology
Matèries:	HNSCC EGFR Sortilin pro-NGF NGF survival
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fonc.2023.661775/full
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