Type B insulin resistance with glycemic extremes: a case report and literature review

BackgroundType B insulin resistance (TBIR) is a rare autoimmune disorder caused by immunoglobulin G (IgG) autoantibodies targeting the insulin receptor. These antibodies act as partial agonists, resulting in severe insulin resistance and hyperglycemia at high titer, and hypoglycemia at low titer. TB...

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Κύριοι συγγραφείς:	Emmeline Monique T. Ngo, Jordan M. Rowe, Thilo Samson Chillon, Lutz Schomburg, Rebecca J Brown, Shourya Tadisina
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Frontiers Media S.A. 2026-05-01
Σειρά:	Frontiers in Endocrinology
Θέματα:	anti-insulin receptor autoantibody GLP-1 receptor agonists insulin receptor antibody rituximab severe insulin resistance Type B insulin resistance
Διαθέσιμο Online:	https://www.frontiersin.org/articles/10.3389/fendo.2026.1852784/full
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