Comparative analysis of the ex vivo IFN-gamma responses to CD8+ T cell epitopes within allelic forms of PfAMA1 in subjects with natural exposure to malaria.

Antigen polymorphisms in essential malarial antigens are a key challenge to the design and development of broadly effective malaria vaccines. The effect of polymorphisms on antibody responses is fairly well studied while much fewer studies have assessed this for T cell responses. This study investig...

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Principais autores:	Omarine N Nlinwe, Ebenezer A Ofori, Kwadwo Akyea-Mensah, Eric Kyei-Baafour, Harini Ganeshan, Maria Belmonte, Bjoern Peters, Eileen Villasante, Martha Sedegah, Kwadwo Asamoah Kusi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2021-01-01
coleção:	PLoS ONE
Acesso em linha:	https://doi.org/10.1371/journal.pone.0257219
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