Abatacept improves posttransplant survival and reduces endothelial injury syndromes in β-thalassemia major
Abstract: Iron overload in transfusion-dependent β-thalassemia (TDT) generates reactive oxygen species, predisposing to post–hematopoietic stem cell transplant (HSCT) endothelial activation. Abatacept prevents acute graft-versus-host disease (GVHD) by inhibiting CD80/CD86 on T cells, but CD80 is als...
שמור ב:
| Principais autores: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Elsevier
2025-12-01
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| סדרה: | Blood Advances |
| גישה מקוונת: | http://www.sciencedirect.com/science/article/pii/S2473952925005750 |
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