PERSIST platform provides programmable RNA regulation using CRISPR endoRNases
Gene circuits must resist epigenetic silencing for reliable therapeutic applications. Here the authors develop an RNA-level regulation platform using CRISPR endoRNases that is modular, scalable, and more stable than traditional transcriptional versions.
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2022-05-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-022-30172-3 |
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