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IFNα subtype-specific susceptibility of HBV in the course of chronic infection

Chronic hepatitis B virus (HBV) infection continues to be a major health problem worldwide and remains hard to be cured. Therapy with interferon (IFN) α is an important method for the clinical treatment of chronic hepatitis B. IFNα exhibits direct antiviral effects as well as immunomodulatory activi...

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Principais autores: Xiaohong Xie, Zehra Karakoese, Dilhumare Ablikim, Julia Ickler, Jonas Schuhenn, Xiaoqing Zeng, Xuemei Feng, Xuecheng Yang, Ulf Dittmer, Dongliang Yang, Kathrin Sutter, Jia Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-10-01
coleção:Frontiers in Immunology
Assuntos:
IFNα subtypes
hepatitis B virus
persistent infection
hydrodynamic injection
IFN induction
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1017753/full
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