Comprehensive Analysis of Senescence Characteristics Defines a Novel Prognostic Signature to Guide Personalized Treatment for Clear Cell Renal Cell Carcinoma

Accumulating evidence has suggested the impact of senescence on tumor progression, but no report has yet described how senescence shapes the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The objective of this study was to delineate the senescence features of ccRCC and its role i...

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Hlavní autoři:	Peng Zhou, Zheng Liu, Henglong Hu, Yuchao Lu, Jun Xiao, Yanan Wang, Yang Xun, Qidong Xia, Chenqian Liu, Jia Hu, Shaogang Wang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-06-01
Edice:	Frontiers in Immunology
Témata:	cellular senescence tumor microenvironment prognostic signature targeted therapy immune checkpoint blockade
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.901671/full
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