Activation function 1 of progesterone receptor is required for mammary development and regulation of RANKL during pregnancy
Abstract Progesterone receptor (PGR) is a member of the nuclear receptor superfamily of transcription factors. It is critical for mammary stem cells expansion, mammary ductal branching and alveologenesis. The transcriptional activity of PGR is mainly mediated by activation functions AF1 and AF2. Alt...
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| Principais autores: | , , , , |
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| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
Nature Portfolio
2022-07-01
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| 丛编: | Scientific Reports |
| 在线阅读: | https://doi.org/10.1038/s41598-022-16289-x |
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