Deficiency of TOP1MT enhances glycolysis through the stimulation of PDK4 expression in gastric cancer
Abstract Background Abnormal glucose metabolism is one of the determinants of maintaining malignant characteristics of cancer. Targeting cancer metabolism is regarded as a new strategy for cancer treatment. Our previous studies have found that TOP1MT is a crucial gene that inhibits glycolysis and ce...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2024-01-01
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| coleção: | Cancer & Metabolism |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s40170-024-00330-w |
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