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Gold-catalyzed direct alkynylation of tryptophan in peptides using TIPS-EBX

The selective functionalization of peptides containing only natural amino acids is important for the modification of biomolecules. In particular, the installation of an alkyne as a useful handle for bioconjugation is highly attractive, but the use of a carbon linker is usually required. Herein, we r...

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Autors principals: Gergely L. Tolnai, Jonathan P. Brand, Jerome Waser
Format: Artigo
Idioma:Inglês
Publicat: Beilstein-Institut 2016-04-01
Col·lecció:Beilstein Journal of Organic Chemistry
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Accés en línia:https://doi.org/10.3762/bjoc.12.74
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