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CD73 mediates the therapeutic effects of endometrial regenerative cells in concanavalin A-induced hepatitis by regulating CD4+ T cells

Abstract Background As a kind of mesenchymal-like stromal cells, endometrial regenerative cells (ERCs) have been demonstrated effective in the treatment of Concanavalin A (Con A)-induced hepatitis. However, the therapeutic mechanism of ERCs is not fully understood. Ecto-5`-nucleotidase (CD73), an en...

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Hlavní autoři: Hong Qin, Chenglu Sun, Dejun Kong, Yanglin Zhu, Bo Shao, Shaohua Ren, Hongda Wang, Jingyi Zhang, Yini Xu, Hao Wang
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2023-09-01
Edice:Stem Cell Research & Therapy
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On-line přístup:https://doi.org/10.1186/s13287-023-03505-2
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