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A single center analysis of nucleophosmin in acute myeloid leukemia: value of combining immunohistochemistry with molecular mutation analysis

Mutations of nucleophosmin 1 are frequently found in acute myeloid leukemia and lead to aberrant cytoplasmic accumulation of nucleophosmin protein. Immunohistochemical staining is therefore recommended as the technique of choice in front-line screening. In this study, we assessed the sensitivity and...

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Principais autores: Carolien M. Woolthuis, André B. Mulder, Rikst Nynke Verkaik-Schakel, Stefano Rosati, Arjan Diepstra, Eva van den Berg, Jan Jacob Schuringa, Edo Vellenga, Philip M. Kluin, Gerwin Huls
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2013-10-01
Serija:Haematologica
Online dostop:https://haematologica.org/article/view/6803
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