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HIV-1 and HIV-2 interaction results in reduced cell infectivity and viral replication in vitro

Abstract Background During dual infection, HIV-1 and HIV-2 may infect the same cell, either simultaneously or sequentially. When these closely related lentiviruses co-infect, HIV-2 has been found to inhibit HIV-1 replication in vitro. In-patient infection data suggests that dual infection attenuates...

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Autori principali: Edwin Magomere, Mark Appeaning, Nana-Ama Amoako, Alberta Serwaa, Kirk Kouffie, Enoch Matey Langmer, Samuel Effah, Thibault Mesplede, George B. Kyei, Thumbi Ndung’u, Peter Kojo Quashie
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2026-02-01
Serie:Virology Journal
Soggetti:
Dual infections
Disease progression
Infectivity
HIV-1
HIV-2
Viral transcription
Accesso online:https://doi.org/10.1186/s12985-026-03077-6
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