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Potential Crosstalk between the PACAP/VIP Neuropeptide System and Endoplasmic Reticulum Stress—Relevance to Multiple Sclerosis Pathophysiology

Multiple sclerosis (MS) is an immune-mediated disorder characterized by focal demyelination and chronic inflammation of the central nervous system (CNS). Although the exact etiology is unclear, mounting evidence indicates that endoplasmic reticulum (ER) stress represents a key event in disease patho...

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Principais autores: Minduli Withana, Alessandro Castorina
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-11-01
Serier:Cells
Fag:
pituitary adenylate cyclase-activating polypeptide (PACAP)
vasoactive intestinal peptide (VIP)
endoplasmic reticulum (ER) stress
unfolded protein response (UPR)
multiple sclerosis
neuroinflammation
Online adgang:https://www.mdpi.com/2073-4409/12/22/2633
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