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Environmentally induced transgenerational epigenetic reprogramming of primordial germ cells and the subsequent germ line.

A number of environmental factors (e.g. toxicants) have been shown to promote the epigenetic transgenerational inheritance of disease and phenotypic variation. Transgenerational inheritance requires the germline transmission of altered epigenetic information between generations in the absence of dir...

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Principais autores: Michael K Skinner, Carlos Guerrero-Bosagna, M Haque, Eric Nilsson, Ramji Bhandari, John R McCarrey
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2013-01-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC3712023?pdf=render
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