Investigating the oncogenic potential of MTHFD2 in oral squamous cell carcinoma

Abstract Purpose Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), a mitochondrial bifunctional enzyme, is reportedly upregulated in several malignancies, demonstrating cancer-associated dysregulation. However, its functional contribution to oral squamous cell carcinoma (OSCC) progression remains...

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Bibliografiset tiedot

Päätekijät:	Jiusong Han, Wei Wang, Simin Li, Juan Wang
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Springer 2026-03-01
Sarja:	Journal of Cancer Research and Clinical Oncology
Aiheet:	Methylenetetrahydrofolate dehydrogenase 2 Oral carcinogenesis Cell proliferation Metabolism Therapeutic target
Linkit:	https://doi.org/10.1007/s00432-026-06451-7
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